Machine learning-guided protein engineering to improve the catalytic activity of transaminases under neutral pH conditions

Si-Han Liu, Ligai Bai,* Xu-Dong Wang, Qi-Qiang Wang, De-Xian Wang, Uwe T. Bornscheuer, Yu-Fei Ao* Org. Chem. Front. 2025, DOI: 10.1039/d5qo00423c

Barbiturate-containing macrocycles: Synthesis, structure and anion recognition through anion-carbonyl interactions

Jun Zhu, Xu-Dong Wang,* Yu-Fei Ao, Qi-Qiang Wang, De-Xian Wang* Sci. China Chem. 2025, DOI: 10.1007/s11426-025-2637-2

Dicarboxylate recognition based on ultracycle hosts through cooperative hydrogen bonding and anion–π interactions

Wen-Hui Mi, Teng-Yu Huang, Xu-Dong Wang, Yu-Fei Ao, Qi-Qiang Wang,* De-Xian Wang* Beilstein J. Org. Chem. 2025, 21, 884-889.

C₃-symmetric aromatic triimides as useful building blocks for supramolecular chemistry and advanced materials

De-Hui Tuo, Xu-Dong Wang,* De-Xian Wang* Chem. Soc. Rev. 2025, 54, 3535-3556.

Cooperative anion–π catalysis with chiral molecular cages toward enantioselective desymmetrization of anhydrides

Ming-Sen Yue, Na Luo, Xu-Dong Wang, Yu-Fei Ao, De-Xian Wang, Qi-Qiang Wang* J. Am. Chem. Soc. 2025, 147, 2303-2308.

(ICCAS Research Progress News;  Featured in X-MOL)