敖宇飞 副研究员 敖宇飞 副研究员

最小化 最大化

敖宇飞 副研究员

学习与工作经历

2003 - 2007  北京师范大学 获得学士学位

2008 - 2014  中国科学院化学研究所 获得博士学位(师从王梅祥教授)

2014 - 2019  中国科学院化学研究所 助理研究员

2019 - 至今   中国科学院化学研究所 副研究员

 

研究领域

生物催化

 

联系方式

中国科学院化学研究所分子识别与功能院重点实验室

地址:北京市海淀区中关村北一街2号5#1015   邮编: 100190

邮箱:aoyufe@iccas.ac.cn

电话:010-62565610

传真:010-62564723

ORCID:0000-0002-9415-2181

 

发表论文

Hui-Juan Hu, Peng Chen, Yu-Fei Ao,* Qi-Qiang Wang, De-Xian Wang, Mei-Xiang Wang, "Highly Efficient Biocatalytic Desymmetrization of Meso Carbocyclic 1,3-Dicarboxamides: A Versatile Route for Enantiopure 1,3-Disubstituted Cyclohexanes and Cyclopentanes", Org. Chem. Front. 2019, 6, 808-812.

Yu-Fei Ao,* Li-Bin Zhang, Qi-Qiang Wang, De-Xian Wang, Mei-Xiang Wang, "Biocatalytic desymmetrization of prochiral 3-aryl and 3-arylmethyl glutaramides: Different remote substituent effect on catalytic efficiency and enantioselectivity", Adv. Synth. Catal. 2018, 360, 4594-4603.

敖宇飞,* 王其强,王德先. "有机合成中腈的去对称化生物转化反应研究进展", Chin. J. Org. Chem.2016, 36, 2333-2343.

Yu-Fei Ao, De-Xian Wang, Liang Zhao, Mei-Xiang Wang*, "Synthesis of quaternary carbon-containing and functionalized enantiopure 3-carbamoylcyclo-pentanecarboxylic acids from biocatalytic enantioselective desymmetrization of meso cyclopentane-1,3-dicarboxamides", Chem. Asian J. 2015, 10, 938-947.

Yu-Fei Ao, De-Xian Wang, Liang Zhao, Mei-Xiang Wang*, "Biotransformations of racemic 2,3-allenenitriles in biphasic systems: Synthesis and transfor-mations of enantioenriched axially chiral 2,3-allenoic acids and their derivatives", J. Org. Chem. 2014, 79, 3103-3110.

Yu-Fei Ao, Dong-Hui Leng, De-Xian Wang, Liang Zhao, Mei-Xiang Wang*, "Efficient synthesis of highly enantiopure β-lactam derivatives from biocatalytic transformations of amides and nitriles", Tetrahedron 2014, 70, 4309-4316.